Indication:
Avapritinib generic AYVAKIT is a prescription medicine used to treat Gastrointestinal stromal tumor (GIST) is a cancer that originates in the walls of the digestive tract. Avapritinib is also indicated for certain forms of mastocytosis, a blood disorder characterized by the excessive accumulation of mast cells, a type of white blood cell, in the body.
You can take this medicine if:
Avapritinib, marketed under the brand name AYVAKIT, is a prescription medication primarily used to treat Gastrointestinal Stromal Tumors (GIST), a rare and aggressive type of cancer that forms in the tissues of the digestive tract, most often in the stomach or small intestine. This cancer arises from abnormal growth in the interstitial cells of Cajal, which play a key role in regulating muscle contractions in the digestive system. Avapritinib is particularly effective in treating GISTs that have mutations in a specific gene called KIT or PDGFRA, which contribute to the uncontrolled growth of the tumor. In addition to its role in treating GIST, Avapritinib is also prescribed for certain forms of mastocytosis, a rare blood disorder. Mastocytosis is characterized by an overproduction of mast cells, which are a type of white blood cell involved in allergic reactions and immune responses. In mastocytosis, these cells accumulate in various organs, leading to symptoms ranging from skin rashes to more severe complications involving the digestive tract, liver, spleen, or bone marrow. Avapritinib works by targeting and inhibiting specific enzymes in the body that promote the abnormal growth of both mast cells and tumor cells, helping to manage and reduce symptoms associated with these conditions.
Dosage:
What is the dosage of Avapritinib?
Avapritinib has to take orally once daily.
The dosage of Avapritinib (AYVAKIT) depends on the condition being treated and the individual patient’s health status. For Gastrointestinal Stromal Tumors (GIST) with a specific genetic mutation, the recommended dose is typically 300 mg taken once daily, but the dose may be adjusted based on how the patient responds to treatment or any side effects they experience. For patients with advanced forms of mastocytosis, the usual starting dose is 200 mg per day, again taken once daily, but this can also be increased or decreased depending on the patient’s tolerance and response. It is important to follow the doctor’s prescribed dosage closely, as adjusting the dose without medical guidance can affect the effectiveness and safety of the medication. Additionally, patients should be monitored regularly for any side effects, as Avapritinib can cause adverse reactions like fatigue, nausea, or changes in blood cell counts. As a precaution, this medication should not be taken with strong CYP3A inhibitors or in combination with other drugs that could interact negatively. Always consult a healthcare provider before making any changes to the dosage.
Extra Notes:
Patients should avoid missing doses, but if a dose is missed, they should take it as soon as they remember, unless it’s close to the time for the next dose. Double dosing is not recommended. Regular medical check-ups are essential to ensure the medication is working as expected and to monitor for any potential side effects.
Side Effect:
What is the most common adverse reactions/ side effects of Avapritinib?
Edema (swelling), Nausea, Fatigue/asthenia, Cognitive impairment, Vomiting, Decreased appetite, Diarrhea, Hair color changes, Increased lacrimation (tear production), Abdominal pain, Constipation, Rash, Dizziness.
The above information comes from the Internet. Please consult with a doctor for medical advice.
FAQ about (Avapritinib)/ AYVAKIT Generic Avapritinib:
Q. Is (Avapritinib)/ AYVAKIT Generic Avapritinib available to supply worldwide?
Yes! We can supply (Avapritinib) worldwide. According to WTO rules and regulations, we can supply our prescription medicine in most of the country for patient’s personal use.
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Avapritinib has different brand names depending on the manufacturer. Some of the brand names are:
Avapritinib (Luciavap 100mg) Rx
Anti Cancer