Indication:

Fluvoxamine Maleate generic Luvox is a prescription medicine used to treat of obsessive-compulsive disorder (OCD), a psychiatric condition characterized by persistent, intrusive thoughts (obsessions) and repetitive behaviors or mental acts (compulsions) performed in response to these thoughts.

You can take this medicine if:

Fluvoxamine maleate is a selective serotonin reuptake inhibitor (SSRI) primarily indicated for the treatment of obsessive-compulsive disorder (OCD) in adults and children aged eight years and older. By inhibiting the reuptake of serotonin in the brain, fluvoxamine helps to restore the balance of this neurotransmitter, thereby reducing the frequency and severity of obsessive thoughts and compulsive behaviors. It is also used in the management of other psychiatric conditions such as major depressive disorder (MDD), social anxiety disorder, and panic disorder, although these uses may vary depending on regional regulatory approvals.

In addition to its psychiatric applications, fluvoxamine has recently been investigated for its potential role in the treatment of COVID-19 due to its anti-inflammatory and sigma-1 receptor agonist properties, which may modulate the body’s immune response and reduce cytokine-related damage. While not formally approved for this indication, some clinical studies have suggested potential benefits in reducing disease progression in early stages of infection. Like other SSRIs, fluvoxamine requires careful dose management and monitoring for side effects such as nausea, insomnia, and the risk of serotonin syndrome, especially when used concurrently with other serotonergic agents.

Dosage:

Fluvoxamine Maleate has to take orally once daily at bedtime.

The dosage of Fluvoxamine Maleate varies depending on the indication, patient age, and clinical response. For adults with obsessive-compulsive disorder (OCD), the recommended initial dose is 50 mg once daily at bedtime, which may be increased gradually in increments of 50 mg every 4 to 7 days based on therapeutic response and tolerability, up to a maximum daily dose of 300 mg, usually administered in divided doses for amounts exceeding 100 mg. In children and adolescents (ages 8–17) with OCD, the initial dose is typically 25 mg at bedtime, with gradual titration up to a maximum of 200 mg/day, also given in divided doses if necessary. Fluvoxamine should be taken with food to reduce gastrointestinal side effects, and dose adjustments may be required in patients with hepatic impairment due to its metabolism via the liver.

Note:

Fluvoxamine should be tapered gradually when discontinuing to minimize withdrawal symptoms. It has significant potential for drug interactions, particularly through inhibition of cytochrome P450 enzymes (notably CYP1A2 and CYP2C19), and caution is warranted when used with other serotonergic agents or central nervous system drugs. Clinical monitoring is essential, especially during initial dose adjustments or when used in populations at risk for suicide.

Side Effect:

The most common adverse reactions of Fluvoxamine Maleate are:

Nausea, Drowsiness or insomnia, Dry mouth, Dizziness, Headache, Loss of appetite, Sweating, Constipation or diarrhea, Sexual dysfunction.

The above information comes from the Internet. Please consult with a doctor for medical advice.

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FLUVOXAMINE MALEATE has different brand names depending on the manufacturer. Some of the brand names are: