Glecaprevir + Pibrentasvir, generic MAVYRET is a prescription medicine used to treat chronic hepatitis C virus (HCV; a viral infection of the liver) genotype (GT) 1, 2, 3, 4, 5 or 6 infection without cirrhosis and with compensated cirrhosis (Child-Pugh A). This is a fixed-dose combination of glecaprevir, a hepatitis C virus (HCV) NS3/4A protease inhibitor, and pibrentasvir, an HCV NS5A inhibitor. Glecaprevir + Pibrentasvir is also indicated for the treatment of adult patients with HCV genotype 1 infection, who previously have been treated with a regimen containing an HCV NS5A inhibitor or an NS3/4A protease inhibitor, but not both.
Hepatitis B virus (hep B) coming back: Your doctor will do blood tests to see if you have hep B infection before you start taking MAVYRET. If you have previously had hepatitis B, it may recur during or after MAVYRET therapy for hepatitis C. Reactivation of Hepatitis B can result in significant liver issues, including liver failure and death. Your doctor will watch you if you have a chance of hep B coming back during and after your treatment with MAVYRET.
Glecaprevir + Pibrentasvir has to take orally Once daily with food.
If you are using the pellet form of this medication, first put about 1 to 2 teaspoons of soft food in a container. Use soft foods that can stick to a spoon (such as peanut butter, chocolate hazelnut spread, cream cheese, thick jam, or Greek yogurt). Do not use any foods that are hard, watery, hot, or cold. Before opening, gently shake the packet and tap it to ensure the pellets fall to the bottom. Cut the packet(s) open and place the dose in the soft food container. Gently combine and provide the entire dosage immediately. Without chewing or crushing, the combination should be consumed within 15 minutes. If you chew, crush, or wait to give the dose, it may make this medication taste bad and not work as well.
FAQ about (GLECAPREVIR + PIBRENTASVIR)/ MAVYRET Generic GLECAPREVIR + PIBRENTASVIR:
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GLECAPREVIR + PIBRENTASVIR has different brand names depending on the manufacturer. Some of the brand names are: