PEGFILGRASTIM is a prescription medicine used to treat help your body make more white blood cells. White blood cells are important to help you fight off infections. Pegfilgrastim is given to people whose ability to make white blood cells is reduced due to chemotherapy. Some brands may also be used to increase white blood cells after exposure to large amounts of radiation.
Pegfilgrastim is a drug that has been approved by the FDA to lower the chance of patients getting febrile neutropenia, a condition where they have a fever and low white blood cell count, when they are getting chemotherapy that can harm their bone marrow. The drug should only be used for primary prevention when the chance of getting febrile neutropenia is 20% or more, and when there is no other chemotherapy that is as effective and safer for the patient. Pegfilgrastim is a modified version of filgrastim, which is a man-made copy of G-CSF, a natural substance that makes the bone marrow produce more white blood cells called neutrophils. These cells help fight infections. Pegfilgrastim has been changed by adding a substance called polyethylene glycol (PEG), which makes it last longer in the body and reduces the need for frequent injections.
PEGFILGRASTIM has to take by injection under the skin as directed by your doctor. For use during chemotherapy.
Your doctor will decide how much and how often you need to take this medication based on your condition and how you respond to it. The amount of medication for children also depends on their weight.
If you are giving yourself this medication at home, follow the directions from your health care professional and the product package on how to prepare and use it. Before using it, take the medication out of the refrigerator. Let it reach room temperature, usually for at least 30 minutes. Do not warm up this medication in any other way, such as by microwaving or putting in hot water. Do not shake this medication. Look at this product carefully for any particles or discoloration. If you see any, do not use the liquid.
Before you inject each dose, clean the area where you will inject with rubbing alcohol. Use a different spot each time you inject to avoid damage under the skin. Do not inject pegfilgrastim into skin that has bruises, pain, redness, hardness, or scars, moles, or stretch marks.
The most common adverse reactions of PEGFILGRASTIM are:
Aching or pain in the bones and muscles.
The above information comes from the Internet. Please consult with doctor for medical advice.
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