Indication:

Pimecrolimus generic ELIDEL is a prescription medicine used to treat of mild to moderate atopic dermatitis (a form of eczema) in immunocompetent individuals. Pimecrolimus is typically prescribed when conventional topical therapies are either ineffective or not advisable for use.

You can take this medicine if:

Pimecrolimus is a topical immunomodulatory agent indicated for the treatment of mild to moderate atopic dermatitis (eczema), particularly in patients for whom conventional therapies such as topical corticosteroids are either not appropriate or have not been effective. It belongs to the class of calcineurin inhibitors and works by inhibiting the activation of T-cells and the subsequent release of inflammatory cytokines, thereby reducing inflammation, redness, and itching associated with eczema. Pimecrolimus is especially useful in sensitive skin areas such as the face, neck, and skin folds, where long-term corticosteroid use may be problematic due to the risk of skin thinning.

It is approved for use in non-immunocompromised patients aged 2 years and older and is typically applied as a thin layer to affected areas twice daily. Unlike corticosteroids, pimecrolimus does not cause skin atrophy, making it suitable for long-term, intermittent use to manage flare-ups and maintain disease control. However, its use should be limited to short-term and non-continuous long-term treatment, and it is recommended to avoid use in cases of active infection. Due to concerns regarding a potential risk of malignancy (e.g., skin cancer and lymphoma), a black box warning is associated with its use, and it should be prescribed with caution, ensuring appropriate patient selection and monitoring.

Dosage:

have to apply a thin layer to the affected areas of skin as directed by your doctor, usually twice daily. Avoid use in children under 2 years old and on large areas of skin or broken skin. For topical use only. Not for ophthalmic, oral, or intravaginal use.

The recommended dosage of Pimecrolimus 1% cream is to apply a thin layer to the affected skin areas twice daily, typically in the morning and evening, for the treatment of mild to moderate atopic dermatitis in non-immunocompromised patients aged 2 years and older. Treatment should begin at the first signs of symptoms such as redness, itching, or inflammation, and continued until the clearance of eczema lesions. The cream should be gently rubbed into the skin and not used under occlusive dressings. Pimecrolimus is intended for intermittent, short-term use and can be resumed upon the reappearance of symptoms to help manage flares effectively.

Note:

Pimecrolimus should not be used on infected or broken skin, and patients should avoid exposure of treated areas to natural or artificial sunlight, including tanning beds. It is not recommended for continuous long-term use due to a potential, though unproven, risk of malignancy, including skin cancer and lymphoma, which is reflected in a black box warning. If no improvement is observed within six weeks, clinical re-evaluation is advised. Patients should be educated on proper application techniques and the importance of sun protection during treatment.

Side Effect:

The most common adverse reactions of Pimecrolimus are:

Skin irritation or redness, Burning​​.

The above information comes from the Internet. Please consult with a doctor for medical advice.

FAQ:

FAQ about (PIMECROLIMUS)/ ELIDEL Generic PIMECROLIMUS:

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PIMECROLIMUS has different brand names depending on the manufacturer. Some of the brand names are: