Selinexor, generic XPOVIO is a prescription medicine used to treat Multiple Myeloma, Diffuse Large B-Cell Lymphoma cancer. Selinexor works by slowing or stopping the growth of cancer cells.
Selinexor is a medicine that doctors prescribe to treat:
adults with multiple myeloma who have had at least one previous treatment, together with bortezomib and dexamethasone.
adults with multiple myeloma that has returned (relapsed) or that did not get better with previous treatment (refractory), and
who have had at least 4 previous treatments, and
whose disease did not get better (refractory) with at least 2 medicines that block proteasomes, at least 2 medicines that affect the immune system, and a medicine that targets CD38
Selinexor is approved based on how patients responded to treatment. There are more studies being done to show the clinical benefit of Selinexor for this use:
to treat adults with some types of diffuse large B-cell lymphoma that has returned (relapsed) or that did not get better with previous treatment (refractory) and who have had at least 2 previous systemic treatments.
No one knows if Selinexor is safe and works well in children under 18 years old.
Selinexor has to take orally 60mg (20mg X 3 tablets) once or twice weekly until disease progression or unacceptable toxicity.
Follow your doctor’s instructions on how to take this medication by mouth, usually once or twice a week. Swallow the tablets whole with water. Do not split, chew, break, or crush the tablets. Drink a lot of fluids while you are taking this medication unless your doctor tells you otherwise.
If you throw up after taking a dose of the medication, do not take another dose. Take the next dose of your medication at the usual time.
The amount of medication you take depends on your medical condition, lab tests, and how you respond to treatment.
The most common adverse reactions of SELINEXOR are:
Dizziness, tiredness, diarrhea, weight loss, nausea, vomiting.
The above information comes from the Internet. Please consult with a doctor for medical advice.
FAQ about (SELINEXOR)/ XPOVIO Generic SELINEXOR:
Q. Is (SELINEXOR)/ XPOVIO Generic SELINEXOR available to supply worldwide?
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SELINEXOR has different brand names depending on the manufacturer. Some of the brand names are: